These days many web designers put an inordinate amount of effort to promote their sites on the search engines. It is just to avoid the situation where the visitor needs to click away from your site just because he is using a different browser. Along with this the main principle is of catering the widest possible audience and designing your web pages for compatibility with different browsers, operating systems and hardware.

The screen resolution matters a lot while creating a website, as it effects on the reputation and growth of the business. The standard screen resolution for a web design is 1024x768 pixels, and if you create some changes in the standard then it might not be clear on the different screen with different resolutions. The option you have is that you can design your website with a fluid design, where the page automatically fits whatever screen resolution the visitor uses.

The different colors gives different results on different screens and systems, depending upon the number of colors in your visitor’s color palettes, their monitor etc. the color that looks beautiful to you thus turns out to be ugly combination on a different system. It is better to use web safe colors while designing a website as they look really good on various screens.